反应详情

温度

80 °C

A mixture of 6.83 g (0.034 mol) of 2-methyl-8H-indeno[2,1-b]thiophen-8-one and 9.1 mL (0.182 mol) of hydrazine monohydrate in 91 mL of diethylene glycol was stirred at 80° C. for 40 min and then refluxed for 1 h. The resulting mixture was cooled to room temperature, treated with a solution of 9.5 g (0.169 mol) of KOH in 34 mL water and then refluxed for 2 h. The resulting mixture was poured into 600 mL of water, the precipitate was filtered, washed 5 times with 200 mL of water and dried. Yield 5.8 g (92%).

1. temperaturerefluxed for 1 h
2. temperatureThe resulting mixture was cooled to room temperature
3. temperaturerefluxed for 2 h
4. filtrationthe precipitate was filtered
5. washwashed 5 times with 200 mL of water
6. customdried