HRID1868723

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2ccc(C#N)cc2C(C)(C)C1=O

HCID67099761

未命名化合物

PRODUCTS

生成物

结构：CC1(C)C(=O)C(C(=O)NCC(=O)O)=C(O)c2ccc(C#N)cc21

HCID67099886

未命名化合物

收率 91.1%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID962

Water

H2O

PROCEDURE

实验过程

1,1-Dimethylethyl N-((7-cyano-4-hydroxy-1,1-dimethyl-2-oxo-naphthalene-3-yl)carbonyl)glycinate (163 mg, 440 μmol) was stirred in TFA (1 mL, 13462 μmol) at room temperature for 20 minutes. Water was added. The resulting precipitate was filtered and washed with water to give the desired product as an off-white solid (126 mg). MS (m/e)=315.1 (M+H)+. Calculated for C16H14N2O5 314.09.

WORKUP

后处理

filtrationThe resulting precipitate was filtered
washwashed with water