Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → N-((7-Cyano-4-hydroxy-1,1-dimethyl-2-oxo-naphthalen-3-yl)carbonyl)glycine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 1,1-Dimethylethyl N-((7-cyano-4-hydroxy-1,1-dimethyl-2-oxo-naphthalene-3-yl)carbonyl)glycinate | HCID 67099761 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-((7-Cyano-4-hydroxy-1,1-dimethyl-2-oxo-naphthalen-3-yl)carbonyl)glycine | HCID 67099886 | 91.1% |
반응 단계
1,1-Dimethylethyl N-((7-cyano-4-hydroxy-1,1-dimethyl-2-oxo-naphthalene-3-yl)carbonyl)glycinate (163 mg, 440 μmol) was stirred in TFA (1 mL, 13462 μmol) at room temperature for 20 minutes. Water was added. The resulting precipitate was filtered and washed with water to give the desired product as an off-white solid (126 mg). MS (m/e)=315.1 (M+H)+. Calculated for C16H14N2O5 314.09.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07635715B2 |
| 출처 데이터셋 | uspto-grants-2009_12 |
| ORD ID | ord-21e9dbb48dac4b0d9e700d6cfd930d02 |
| 출처 메모 | uspto-grants-2009_12 |