HRID1868762

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2ccc(Br)cc2C(C)(C)C1=O

HCID67099764

未命名化合物

PRODUCTS

生成物

结构：CC1(C)C(=O)C(C(=O)NCC(=O)O)=C(O)c2ccc(Br)cc21

HCID57983529

未命名化合物

收率 92.4%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID962

Water

H2O

PROCEDURE

实验过程

1,1-Dimethylethyl N-((7-bromo-4-hydroxy-1,1-dimethyl-2-oxo-naphthalen-3-yl)carbonyl)glycinate (328 mg, 773 μmol) was stirred in TFA (2 mL, 26.9 mmol) at room temperature for 25 minutes. Water was added. The resulting precipitate was filtered and washed with water to give the desired product as an off-white solid (263 mg). MS (m/e)=368.1 (M+H)+. Calculated for C15H14BrNO5 367.01.

WORKUP

后处理

filtrationThe resulting precipitate was filtered
washwashed with water