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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1869065Generated: October 30, 2026

4-Chloro-6,7-dimethoxyquinazoline → HCID 18924998, compound

https://huagongshe.com/reaction/1869065

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-6,7-dimethoxyquinazolineHCID 2769364—
Reactant4-Azidoaniline hydrochlorideHCID 16211210—
SolventIsopropanolHCID 3776—
ProductHCID 18924998HCID 18924998—

Reaction Steps

4-Chloro-6,7-dimethoxyquinazoline (250 mg, 1.12 mmol) and 4-azidoaniline hydrochloride (200 mg, 1.11 mmol) were refluxed in 10 mL of isopropyl alcohol for 0.5 hour, cooled and filtered to afford solid title product which was washed with 10 mL of isopropyl alcohol and dried in vacuo, at 70° C., 392 mg (98%); mp 200°-205° C. (dec).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE041065E1
Source datasetuspto-grants-2009_12
ORD IDord-879e21c3a3434c21afdefa030a2c84ac
Source noteuspto-grants-2009_12