Potassium tert-butoxide → 1,3-Dichloro-5-(3,3-dichloro-allyloxy)-2-[4-(4-fluoro-phenyl)-pent-4-enyloxy]-benzene

Participants

Reaction Conditions

Reaction Steps

84 mg of potassium tert-butylate and 236 mg of methyltriphenylphosphonium bromide are stirred in 6 ml of toluene for 3 hours at 80° C. 200 mg of 4-[2,6-dichloro-4-(3,3-dichloro-allyloxy)-phenoxy]-1-(4-fluoro-phenyl)-butan-1-one in 2 ml of toluene are then added and the mixture is stirred for a further 2 hours at 80° C. The reaction mixture is cooled and filtered and the filtrate is concentrated. After purification over silica gel, the title compound is obtained.

Provenance & Evidence