反应详情

N-Methyl-5-(4-{[1-(1-methylethyl)-4-piperidinyl]methyl}-1-piperidinyl)-2-pyridinecarboxamide was prepared using an analogous process to that described in Examples 10 and 11 from 1,1-dimethylethyl 5-(4-{[1-(1-methylethyl)-4-piperidinyl]methyl}-1-piperidinyl)-2-pyridinecarboxylate (may be prepared as described in Example 4) and methylamine. The compound displayed 1H-NMR and mass spectral data that were consistent with structure. MS electrospray (+ion) 359 (MH+).