1,1-Dichloroethane → 1-Cyclopropyl-6-fluoro-8-methoxy-7-{3-[1-(methyl-piperidin-4-yl-amino)-cyclopropyl]-pyrrolidin-1-yl}-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([C:15]2([CH:18]3[CH2:19][N:20]([c:23]4[c:24]([F:42])[cH:25][c:26]5[c:27](=[O:41])[c:28]([C:38](=[O:39])[OH:40])[cH:29][n:30]([CH:35]6[CH2:36][CH2:37]6)[c:31]5[c:32]4[O:33][CH3:34])[CH2:21][CH2:22]3)[CH2:16][CH2:17]2)[CH3:43])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:51][CH:52]([Cl:53])[CH3:54].[OH:44][C:45]([C:46]([F:47])([F:48])[F:49])=[O:50]>>[NH:8]1[CH2:9][CH2:10][CH:11]([N:14]([C:15]2([CH:18]3[CH2:19][N:20]([c:23]4[c:24]([F:42])[cH:25][c:26]5[c:27](=[O:41])[c:28]([C:38](=[O:39])[OH:40])[cH:29][n:30]([CH:35]6[CH2:36][CH2:37]6)[c:31]5[c:32]4[O:33][CH3:34])[CH2:21][CH2:22]3)[CH2:16][CH2:17]2)[CH3:43])[CH2:12][CH2:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-25fdcd220dc9467cb0f5f4bcfe701fc4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…