Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1870202Generated: October 31, 2026

Imidazole → N-[5-(1H-imidazol-1-yl)-4-methyl-2-nitrophenyl]glycine ethyl ester

https://huagongshe.com/reaction/1870202

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
ReactantN-(5-fluoro-4-methyl-2-nitrophenyl)glycine ethyl esterHCID 18695409—
SolventPyridineHCID 1049—
ProductN-[5-(1H-imidazol-1-yl)-4-methyl-2-nitrophenyl]glycine ethyl esterHCID 1869544539.6%

Reaction Steps

By using 1.00 g of N-(5-fluoro-4-methyl-2-nitrophenyl)glycine ethyl ester, 266 mg of imidazole and 10 ml of pyridine, 470 mg (39%) of N-[5-(1H-imidazol-1-yl)-4-methyl-2-nitrophenyl]glycine ethyl ester was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06096743
Source datasetuspto-grants-2000_08
ORD IDord-78bc6a8411cb460baf1d14aa8bc55706
Source noteuspto-grants-2000_08