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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1870211Generated: October 30, 2026

Imidazole → HCID 18695399, compound

https://huagongshe.com/reaction/1870211

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
ReactantN-(4-benzyloxy-5-fluoro-2-nitrophenyl)glycine ethyl esterHCID 18695453—
SolventDimethylformamideHCID 6228—
ProductHCID 18695399HCID 1869539965%

Reaction Steps

By using 448 mg of N-(4-benzyloxy-5-fluoro-2-nitrophenyl)glycine ethyl ester, 350 mg of imidazole and 2 ml of DMF, 331 mg (65%) of N-[4-benzyloxy-5-(1H-imidazol-1-yl)-2-nitrophenyl]glycine ethyl ester was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06096743
Source datasetuspto-grants-2000_08
ORD IDord-c52a89114c514965bc9d601b6103e225
Source noteuspto-grants-2000_08