HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-(N-t-Butoxycarbonylamino)ethoxy)-5-chloro-1,2-benzisoxazole → 3-(2-Aminoethoxy)-5-chloro-1,2-benzisoxazole hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-(N-t-Butoxycarbonylamino)ethoxy)-5-chloro-1,2-benzisoxazole | HCID 15453936 | — |
| Reactant | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| Product | 3-(2-Aminoethoxy)-5-chloro-1,2-benzisoxazole hydrochloride | HCID 18696023 | 190.8% |
Reaction Steps
To 3-(2-(N-t-butoxycarbonylamino)-ethoxy)-5-chloro-1,2-benzisoxazole (0.50 g) was added a solution of 4 N-hydrochloric acid/1,4-dioxane (4.0 ml) and stirred at room temperature for 15 minutes. After filtering the precipitated crystals and washing with 1,4-dioxane, the title compound (0.38 g) was obtained as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06096771 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-5d1bc17ec8e94ee3be2cf1a1818d5cf0 |
| Source note | uspto-grants-2000_08 |