1,4-Dioxane hydrochloride → HCID 69697249, compound

Participants

Reaction Steps

The compound (1.66 g) obtained in Example 108 was dissolved in 1,4-dioxane (20 ml) and thereto was added a 4 N hydrogen chloride/1,4-dioxane solution (1.00 ml), after which the resulting mixture was stirred at room temperature for 2 hours, upon which a white precipitate separated. The reaction mixture was heated to 100° C. to dissolve the precipitate and thereafter allowed to slowly cool with stirring. The resulting white precipitate was separated by filtration to obtain the desired compound (1.19 g).

Provenance & Evidence