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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1870888Generated: November 3, 2026

Phthalide → 2-(4-Bromo-3-methylphenyl)-2,3-dihydroisoindol-1-one

https://huagongshe.com/reaction/1870888

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhthalideHCID 6885—
Reactant4-Bromo-3-methylanilineHCID 23359—
Product2-(4-Bromo-3-methylphenyl)-2,3-dihydroisoindol-1-oneHCID 18694220—

Reaction Steps

The title compound was prepared from 4-bromo-3-methylaniline and phthalide using a similar procedure to Description 20, as a white solid (76%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06100272
Source datasetuspto-grants-2000_08
ORD IDord-2942e97b11cd4411b9bdfc911bd297a0
Source noteuspto-grants-2000_08