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HRID1870903

反应详情

EQUATION

反应方程式

HRID 1870903 的结构方程式

REACTANTS

反应物

2
结构：CN1CC=C(CO)CC1
HCID118921

1,2,3,6-Tetrahydro-1-methylpyridine-4-methanol

C7H13NO

结构：CC(=O)N1CCc2cc(Br)c(O)cc21
HCID18694293

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)N1CCc2cc(Br)c(OCC3=CCN(C)CC3)cc21
HCID18694266

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 1-acetyl-5-bromo-6-hydroxyindoline (D64) and 1-methyl-1,2,5,6-tetrahydropyridine-4-methanol (J. Med. Chem., 1988, 31, 545) using the procedure of Description 8a in WO96/19477. The product was purified by acid/base extraction, then used in the next step.

WORKUP

后处理

  1. customThe product was purified by acid/base extraction