Ammonia → HCID 10852098, compound

Participants

Reaction Steps

Following standard procedure C, the acetate salt of methyl 2-(3'-trifluoromethylphenyl)-1-H-benzimidazole-4-carboxylate (134.8 mg, 0.358 mmol) was treated with excess liquid ammonia in a sealed vessel. The product was purified by recrystallisation from methanol, to yield off-white needles. (78 mg, 72%).

Provenance & Evidence