Diethylamine → HCID 57153238, compound

Participants

Reaction Steps

Compound 6b is preferably synthesized by reacting diethylamine with 2,3-dibromopropene to produce 1-diethylamino-2-bromo-propene. Copper iodide is then added with THF and the mixture is cooled to below about -78° C. The solution is stirred and allowed to gradually rise to room temperature. The mixture may then be opened to air and poured into a solution of saturated ammonium chloride. Compound 6a may then be extracted with, e.g., ether, and dried.

Provenance & Evidence