HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 4-(4-chlorophenyl)-1H-imidazol-1-butanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 2-(4-(4-(4-chlorophenyl)-1H-imidazol-1-yl) butyl)-1H-iso indol-1,3(2H)-dione | HCID 70273486 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(4-chlorophenyl)-1H-imidazol-1-butanamine | HCID 18694779 | — |
Reaction Steps
Using the procedure of Stage B of Example 1, 14.2 g of product of Stage B and 3.6 ml of hydrazine hydrate in 200 ml of ethanol were reacted to obtain 12 g of crude product which was chromatographed on silica (eluant CH2Cl2 --MeOH--NH4OH 8-2-0.04) to obtain the expected product, which is used as is for the synthesis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06100404 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-b9d0b149220c478da9722b45aa0f014e |
| Source note | uspto-grants-2000_08 |