Sodium hydride → HCID 18694783, compound

HRID 1871027Notes

Reaction equation

HRID 1871027 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[N:10]=[CH:11][NH:12][CH:13]=1.[H-].[Na+].Br[CH2:17][CH2:18][CH2:19][CH2:20][N:21]1C(=O)C2=CC=CC=C2C1=O>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[N:10]=[CH:11][N:12]([CH2:17][CH2:18][CH2:19][CH2:20][NH2:21])[CH:13]=1

Participants

4

Reactant 3

HCID 24758Sodium hydrideHCID 93575N-(4-Bromobutyl)phthalimideHCID 178489322HCID 178489322, compound

Product 1

HCID 18694783HCID 18694783, compoundYield 72.8%

Procedure

Using the procedure of Stage A of Example 1, 6 g of the product of Stage A, 1.99 g of sodium hydride and 9.93 g of N-4-bromobutyl phthalimide were reacted to obtain 6.15 g of the expected product.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-cc7497c2d6c948e6ab2f75967083fc59
Source dataset
uspto-grants-2000_08
Patent number
US06100404

Reaction notes

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