反应详情

温度

60 °C

To a solution of diethylfluorene (22.2 g., 0.1 mol.) in propylene carbonate (100 ml), N-bromosuccinimide (17.8 g., 0.1 mol.) was added at 57° C. in portions and the mixture was stirred for 30 minutes at 60° C. The mixture was diluted with 1200 ml of water and extracted with 500 ml of toluene. The toluene extract was washed 3 times with 300 ml portions of water, dried and concentrated. The crude product from 3 batches of the same size totaled 117 g. oil. This was distilled at 2 mm. The first fraction, b.p. 90-93° C., 22.33 g., was found to be propylene carbonate. The second fraction, b. p. 155-165° C., 81.0 g. (89.7% yield), was the desired compound. Mass Spec: m/z 300, 302 (M+).

1. extractionextracted with 500 ml of toluene
2. extractionThe toluene extract
3. washwas washed 3 times with 300 ml portions of water
4. customdried
5. concentrationconcentrated
6. distillationThis was distilled at 2 mm