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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871203Generated: November 3, 2026

4-Hydroxybenzoic Acid → Benzoic acid, 4-(acetyloxy)-

https://huagongshe.com/reaction/1871203

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxybenzoic AcidHCID 135—
ReactantAcetic AcidHCID 176—
CatalystSulfuric AcidHCID 1118—
SolventWaterHCID 962—
ProductBenzoic acid, 4-(acetyloxy)-HCID 16865—

Reaction Conditions

Temperature80 °C

Reaction Steps

6 Grams of 4-hydroxybenzoic acid and 8.2 g of anhydrous acetic acid were placed in a two-necked flask and mixed. While the mixture was cooled with water, 5 drops of sulfuric acid was added. After termination of heat generation, the mixture was heated at 80° C. for 30 minutes. Then, the reaction mixture was poured into cold water, and a precipitated crystal was filtered.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103517
Source datasetuspto-grants-2000_08
ORD IDord-20fbf0f381764177b0bf1f8430bf20aa
Source noteuspto-grants-2000_08