Sulfur dichloride → 3-(Cyclopentyloxy)-4-methoxybenzoyl chloride

HRID 1871265Notes

Reaction equation

HRID 1871265 reaction equation
[CH:1]1([O:6][C:7]2[CH:8]=[C:9]([CH:13]=[CH:14][C:15]=2[O:16][CH3:17])[C:10](O)=[O:11])[CH2:5][CH2:4][CH2:3][CH2:2]1.S(Cl)[Cl:19]>C1(C)C=CC=CC=1>[CH:1]1([O:6][C:7]2[CH:8]=[C:9]([CH:13]=[CH:14][C:15]=2[O:16][CH3:17])[C:10]([Cl:19])=[O:11])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 25353Sulfur dichlorideHCID 27793233-(Cyclopentyloxy)-4-methoxybenzoic acid

Product 1

HCID 27946003-(Cyclopentyloxy)-4-methoxybenzoyl chlorideYield 98%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

54 g of 3-cyclopentyloxy-4-methoxybenzoic acid was added to 30 ml of thiochloride and was stirred for 5 hours. 50 ml of toluene was added to the reaction solution and was concentrated under reduced pressure to obtain 58 g of the dense brown title compound (yield: 98%).

Workup

  1. concentrationwas concentrated under reduced pressure

Sources & evidence

ORD record
ord-2df23536e2ef44cbb85bce58274da44d
Source dataset
uspto-grants-2000_08
Patent number
US06103729

Reaction notes

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