Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871370Generated: November 2, 2026

2-Bromopropane → (cis)-2-isopropyl-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one

https://huagongshe.com/reaction/1871370

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromopropaneHCID 6358—
Reactant(cis)-4-(3,4-Dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 10913208—
Reactant(cis)-4-(3,4-Dimethoxyphenyl)-2-methyl-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 70003942—
Product(cis)-2-isopropyl-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 70002414—

Reaction Steps

Prepared from compound 1 and 2-bromopropane as described for compound 8. Purified by chromatography (dichloromethane). Crystallized from diethyl ether/petroleum ether (60-95° C.). M.p. 79-81° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103718
Source datasetuspto-grants-2000_08
ORD IDord-af068ee46c9443d5b97a95cf0eff0744
Source noteuspto-grants-2000_08