1,6-Dibromohexane → HCID 86755602, compound

HRID 1871381Notes

Reaction equation

HRID 1871381 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[C@H:20]3[C@H:15]([CH2:16][CH2:17][CH2:18][CH2:19]3)[C:14](=[O:21])[NH:13][N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[Br:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]Br>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[C@H:20]3[C@H:15]([CH2:16][CH2:17][CH2:18][CH2:19]3)[C:14](=[O:21])[N:13]([CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][Br:22])[N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

3

Reactant 2

HCID 123681,6-DibromohexaneHCID 10913208(cis)-4-(3,4-Dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one

Product 1

HCID 86755602HCID 86755602, compound

Procedure

Prepared from compound 1 and 1,6-dibromohexane as described for compound 58. Purified by chromatography [ethyl acetate/petroleum ether (60-80° C.), 1:2]. Crystallized from petroleum ether (60-80° C.). M.p. 74-75° C.

Workup

  1. customPurified by chromatography [ethyl acetate/petroleum ether (60-80° C.), 1:2]
  2. customCrystallized from petroleum ether (60-80° C.)

Sources & evidence

ORD record
ord-47bab99ece2647b597d510abfe29c948
Source dataset
uspto-grants-2000_08
Patent number
US06103718

Reaction notes

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