HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dibromobutane → HCID 86755611, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dibromobutane | HCID 8056 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | (cis)-4-(3,4-Dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one | HCID 10913208 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86755611 | HCID 86755611 | — |
Reaction Steps
15 g of 1,4-dibromobutane was added to a mixture of 5.0 g of compound 1 and 1.0 g of sodium hydride in dimethylformamide. After stirring the resulting mixture for 5 hours, the solvent was evaporated and the residue partitioned between water and ethyl acetate. The ethyl acetate solution was dried over magnesium sulfate and evaporated. The residue was purified by chromatography (dichloromethane). M.p. colourless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06103718 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-6e6e2418f7e04c898bd9300cf6ce8316 |
| Source note | uspto-grants-2000_08 |