HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 70003567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | HCID 70002230 | HCID 70002230 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 70003567 | HCID 70003567 | — |
Reaction Steps
A solution of 2 g of compound 112 and 3 g of imidazole in methanol was left for 18 h at room temperature. After evaporating the solvent, the residue was partitioned between water and ethyl acetate. The organic layer was dried over magnesium sulfate and evaporated. The residue was dissolved in ethyl acetate and filtered over silica. The compound crystallized as the hydrochloride from tetrahydrofuran. M.p. 198°-199° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06103718 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-91be61c55414473a899c7a4d9029dee4 |
| Source note | uspto-grants-2000_08 |