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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871442Generated: November 3, 2026

(Tetrahydro-2H-pyran-4-yl)hydrazine → (cis)-4-(3,4-Dimethoxyphenyl)-2-(tetrahydropyran-4-yl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one

https://huagongshe.com/reaction/1871442

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Tetrahydro-2H-pyran-4-yl)hydrazineHCID 10057480—
Reactant(cis)-4-(3,4-Dimethoxyphenyl)-2-(2-hydroxy-1-ethyl)-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-oneHCID 86755609—
Product(cis)-4-(3,4-Dimethoxyphenyl)-2-(tetrahydropyran-4-yl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-oneHCID 86755631—

Reaction Steps

Prepared from compound C and 4-hydrazinotetrahydropyran as described for compound 35. Crystallized from methanol. M.p. 175°-177° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103718
Source datasetuspto-grants-2000_08
ORD IDord-3215fb063ad84d429105f334f9a0091c
Source noteuspto-grants-2000_08