Glycine methyl ester hydrochloride → HCID 88158691, compound

Participants

Reaction Steps

To a flame dried 250 ml round bottom flask, flushed with Argon, was added glycine methyl ester hydrochloride (10.0 g, 79.64 mmol), benzophenone-imine (13.36 ml, 79.64 mmol) and CH2Cl2 (100 ml). The mixture was stirred at room temperature for 18 hrs, filtered and evaporated to dryness in vacuo. The concentrated yellow oil so obtained was then recrystallized, giving 19.96 g (98.94% yield) of the title product as a white solid.

Provenance & Evidence