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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1871520Generated: November 3, 2026

p-(Trifluoromethoxy)benzenesulphonyl chloride → N-[4-[2-(Propylamino)ethyl)phenyl]-4-(trifluoromethoxy)-benzenesulfonamidehydrochloride

https://huagongshe.com/reaction/1871520

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-(Trifluoromethoxy)benzenesulphonyl chlorideHCID 523102—
ReactantHCID 18691624HCID 18691624—
ProductN-[4-[2-(Propylamino)ethyl)phenyl]-4-(trifluoromethoxy)-benzenesulfonamidehydrochlorideHCID 9887351—

Reaction Steps

Using procedure 4, 4-trifluoromethoxybenzenesulfonyl chloride was added to 2-(4-aminophenyl)ethyl-1-(tert-butoxycarbonyl)propylamine to give the title compound as a solid, m.p. 151-154° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06103766
Source datasetuspto-grants-2000_08
ORD IDord-1ad4270ffba54925a38b6abc3b47ed6f
Source noteuspto-grants-2000_08