Hydrochloric Acid → HCID 131721945, compound

HRID 1871878Notes

Reaction equation

HRID 1871878 reaction equation
[NH:1](C(OC(C)(C)C)=O)[C@H:2]([C:21]([OH:23])=[O:22])[CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[N:6]([NH:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:5]=1.[ClH:31]>O1CCOCC1>[NH2:1][C@H:2]([C:21]([OH:23])=[O:22])[CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[N:6]([NH:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:5]=1.[ClH:31]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 131721947HCID 131721947, compound

Product 1

HCID 131721945HCID 131721945, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Dissolve Boc-Trp(NHBn) (1.97 g, 5 mmol) in a solution of 4N hydrochloric acid in dioxane (10 mL). Stir at room temperature for 30 minutes and evaporate the solvent in vacuo to give Trp(NHBn)·hydrochloride.

Workup

  1. customevaporate the solvent in vacuo

Sources & evidence

ORD record
ord-f9e135b73e1f4a9d9473bfb68898fc83
Source dataset
uspto-grants-2000_08
Patent number
US06107275

Reaction notes

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