HCID 18689938, compound → HCID 18689941, compound

HRID 1871923Notes

Reaction equation

HRID 1871923 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]=[C:12]1[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]1>C(O)C.[C].[Pd]>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][CH:12]1[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1

Participants

4

Reactant 1

HCID 18689938HCID 18689938, compound

Product 1

HCID 18689941HCID 18689941, compound

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

4-(2-Quinolylmethylene)piperidine (9.62 g) was dissolved in ethanol (500 ml), and 10% palladium-carbon (1.9 g) was added to the solution. The mixture was stirred under a hydrogen stream at room temperature for 90 minutes. After removal of the catalyst by filtration, the filtrate was concentrated under reduced pressure, to thereby obtain the title compound as a colorless solid.

Workup

  1. customAfter removal of the catalyst
  2. filtrationby filtration
  3. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-1028fdb0ad1a4cc5b26e5373dedba277
Source dataset
uspto-grants-2000_08
Patent number
US06107308

Reaction notes

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