反应详情

Phosphorous tribromide (5.3 ml) was added to a solution of the product from step (i) (7.6 g) in benzene (150 ml) at 0° C. After 3 hours, water (40 ml) was added and the mixture warmed to room temperature and extracted with ethyl acetate. The organic phase was dried (MgSO4) and evaporated. Purified by chromatography eluting with 2% ethyl acetate in isohexane. Yield 8.0 g.

1. extractionextracted with ethyl acetate
2. dry with materialThe organic phase was dried (MgSO4)
3. customevaporated
4. customPurified by chromatography
5. washeluting with 2% ethyl acetate in isohexane