(+/-)-5-[2-Ethyl-8-methyl-5H-dibenzo[a,d]cyclohepten-5-yl]-2,4(1H,3H)-pyrimidinedione → (+/-) 2-[5-{2-Ethyl-8-methyl-5H-dibenzo[a,d]cyclohepten-5-yl}-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl]-4-pyrimidinecarboxylic acid, (1,1-dimethylethyl) ester

関与物質

役割	名称	HCID	仕込み量
反応物	(+/-)-5-[2-Ethyl-8-methyl-5H-dibenzo[a,d]cyclohepten-5-yl]-2,4(1H,3H)-pyrimidinedione	HCID 22117281	—
反応物	tert-Butyl 2-chloropyrimidine-4-carboxylate	HCID 57063961	—
生成物	(+/-) 2-[5-{2-Ethyl-8-methyl-5H-dibenzo[a,d]cyclohepten-5-yl}-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl]-4-pyrimidinecarboxylic acid, (1,1-dimethylethyl) ester	HCID 131721956	—

The subtitle compound was prepared from the product of step (iii) and the product of example 15 step (vii) by the method of example 19 step (ii).