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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1872206Generated: October 31, 2026

5,7-Difluoro-1H-indole-2-carboxylic acid → (s)-5,7-Difluoro-1h-indole-2-carboxylic acid (1-benzyl-2-oxo-2-thiazolidin-3-yl-ethyl)-amide

https://huagongshe.com/reaction/1872206

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5,7-Difluoro-1H-indole-2-carboxylic acidHCID 16789245—
Reactant(s)-2-Amino-3-phenyl-1-thiazolidin-3-yl-propan-1-oneHCID 53999780—
Product(s)-5,7-Difluoro-1h-indole-2-carboxylic acid (1-benzyl-2-oxo-2-thiazolidin-3-yl-ethyl)-amideHCID 54472052—

Reaction Steps

From 5,7-difluoro-1H-indole-2-carboxylic acid and (S)-2-amino-3-phenyl-1-thiazolidin-3-yl-propan-1-one. mp 175-185° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06107329
Source datasetuspto-grants-2000_08
ORD IDord-9965287e69594587ba9c5bf677391a3e
Source noteuspto-grants-2000_08