反应详情

To a suspension of 5-(4-methylphenyl)barbituric acid (218 mg) in 2 ml of water, kept at 10° C. under stirring, 136 μl of 48% hydrobromic acid are added, then 56 μl of brominr are dropped and the stirring is continued for 3 hours. The precipitate which formed is recovered by filtration and washed with water. then it is dried under vacuum to give 270 mg of the product, m.p. 210-213° C.

1. customkept at 10° C.
2. addition56 μl of brominr are dropped
3. customThe precipitate which formed
4. filtrationis recovered by filtration
5. washwashed with water
6. customthen it is dried under vacuum