HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-(4-Bromo-2,6-dimethylphenoxymethyl)-1-methylpiperidine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-(4-Bromo-2,6-dimethylphenoxymethyl)-1-methylpiperidine | HCID 9948656 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 3-(4-Bromo-2,6-dimethylphenoxymethyl)-1-methylpiperidine hydrochloride | HCID 21184168 | — |
Reaction Steps
The 3-(4-bromo-2,6-dimethylphenoxymethyl)-1 -methylpiperidine was treated with 1N hydrochloric acid in ether, and the precipitated salt was recrystallized from acetonitrile/tert-butyl methyl ether to yield 3-(4-bromo-2,6-dimethylphenoxymethyl)-1-methylpiperidine hydrochloride, m.p. 180.9-183.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06110937 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-fbaecadc41074484b2aac45d9b9608e8 |
| Source note | uspto-grants-2000_08 |