Methyl iodide → HCID 11426171, compound

HRID 1872684Notes

Reaction equation

HRID 1872684 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][N:6]=[CH:7]2.[I:12][CH3:13]>CC(C)=O>[I-:12].[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][N+:6]([CH3:13])=[CH:7]2

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 707665-Aminoisoquinoline

Product 1

HCID 11426171HCID 11426171, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of 5-aminoisoquinoline (14.4 g, 100 mmol) in acetone (300 ml) was added iodomethane (14.4 ml). The solution was briefly stirred and then allowed to sthand for 2h. The yellow precipithate was then filtered, washed with acetone and dried to afford the title compound as a yellow solid (18.8 g).

Workup

  1. filtrationThe yellow precipithate was then filtered
  2. washwashed with acetone
  3. customdried

Sources & evidence

ORD record
ord-1393fedd38a24ce8839b7aed18fa7a4a
Source dataset
uspto-grants-2000_08
Patent number
US06110934

Reaction notes

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