HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 5-Chloro-2,4-dimethoxybenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 5-Chloro-2,4-dimethoxybenzoic acid | HCID 314349 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-Chloro-2,4-dimethoxybenzoyl chloride | HCID 18687442 | — |
Reaction Steps
A solution of 5-chloro-2,4-dimethoxybenzoic acid (6.4 g) in dichloromethane (250 ml) was treated with thionyl chloride (30 ml) and the mixture heated at reflux for 18h. Removal of volatile material in vacuo afforded the title compound as a white solid (6.6 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06110934 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-100a7975bfce428e8b4580bee5456d0b |
| Source note | uspto-grants-2000_08 |