HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 22597763, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 2-Methoxy-4-(propan-2-yl)benzoic acid | HCID 12613737 | — |
| Reactant | 4-tert-Butyl-2-methoxybenzoic acid | HCID 12613739 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 22597763 | HCID 22597763 | — |
Reaction Steps
To a solution of 2-methoxy-4-iso-propyl benzoic acid (prepared in an analogous manner to Preparation 37, 4-tert-butyl-2-methoxy benzoic acid) (7.0 g, 36.0 mmol) in chloroform (100 ml) was added bromine (1.86 ml) in chloroform (20 ml) dropwise. The reaction was stirred at room temperature overnight. Evaporation in vacuo afforded an oil (9.27 g). m /z (CI): 275, 273 (MH+ ; 70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06110934 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-19894fa651b54de497338116275ac609 |
| Source note | uspto-grants-2000_08 |