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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1872719Generated: November 3, 2026

5-Chloro-2-methoxy-4-nitrobenzoic acid → N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-chloro-2-methoxy-4-nitrobenzamide

https://huagongshe.com/reaction/1872719

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-2-methoxy-4-nitrobenzoic acidHCID 13785669—
Reactant2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amineHCID 14171269—
ProductN-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-chloro-2-methoxy-4-nitrobenzamideHCID 18687433—

Reaction Steps

The title compound was prepared in an analogous manner to Example 1 from 5-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline and 5-chloro-2-methoxy-4-nitrobenzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06110934
Source datasetuspto-grants-2000_08
ORD IDord-4d41b0099f2f466eabf0cd8106ae4943
Source noteuspto-grants-2000_08