Methylamine → HCID 54466087, compound

HRID 1872791Notes

Reaction equation

HRID 1872791 reaction equation
[OH:1][C@@H:2]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[CH2:3][C:4](OC)=[O:5].[CH3:21][NH2:22]>CO>[CH3:21][NH:22][C:4](=[O:5])[CH2:3][C@@H:2]([OH:1])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 12201888HCID 12201888, compound

Product 1

HCID 54466087HCID 54466087, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

(S)-Methyl 3-hydroxyhexadecanoate (1.0 g) was dissolved in a solution of 40% methylamine in methanol (15 ml). This mixture was stirred at room temperature for 2 hours. The resulting crystalline solid was collected by filtration to give (S)-N-methyl-3-hydroxyhexadecanamide (0.71 g).

Workup

  1. filtrationThe resulting crystalline solid was collected by filtration

Sources & evidence

ORD record
ord-7a5f05e05953466caddcead6b645fc1e
Source dataset
uspto-grants-2000_08
Patent number
US06110933

Reaction notes

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