HCID 54107403, compound → HCID 53868867, compound

HRID 1872795Notes

Reaction equation

HRID 1872795 reaction equation
[N:1]([C@@H:4]([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH2:5][C:6]([NH2:8])=[O:7])=[N+]=[N-]>[Pd]>[NH2:1][C@@H:4]([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH2:5][C:6]([NH2:8])=[O:7]

Participants

3

Reactant 1

HCID 54107403HCID 54107403, compound

Product 1

HCID 53868867HCID 53868867, compoundYield 68.3%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

A mixture of (S)-3-azidohexadecanamide (0.17 g) and 10% palladium on carbon (20 mg) was hydrogenated at atmospheric pressure for 5 hours. The catalyst was filtered off with celite, and the filtrate was concentrated under reduced pressure. The residue was recrystallized from ethyl acetate (3 ml) to give (S)-3-aminohexadecanamide (106 mg).

Workup

  1. filtrationThe catalyst was filtered off with celite
  2. concentrationthe filtrate was concentrated under reduced pressure
  3. customThe residue was recrystallized from ethyl acetate (3 ml)

Sources & evidence

ORD record
ord-1396332d6bd8465fb69820c96fe977fc
Source dataset
uspto-grants-2000_08
Patent number
US06110933

Reaction notes

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