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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1872832Generated: November 1, 2026

4-(5-Fluoro-1H-indol-3-YL)cyclohexanone → 4-(6-Fluoro-1H-indol-3-YL)cyclohexanone

https://huagongshe.com/reaction/1872832

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(5-Fluoro-1H-indol-3-YL)cyclohexanoneHCID 10704683—
Reactant3-(1,4-Dioxa-spiro[4,5]dec-8-yl)-6-fluoro-1H-indoleHCID 18414086—
Product4-(6-Fluoro-1H-indol-3-YL)cyclohexanoneHCID 15481281—

Reaction Steps

This compound was prepared in the manner as described above for (3a) by replacing 4-(5-fluoro-1H-3-indolyl)-cyclohexanone ethylene ketal with 4-(6-fluoro-1H-3-indolyl)-cyclohexanone ethylene ketal (5.4 g) in 99% (19.3 g) yield as a white solid: mp 102-105° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06110956
Source datasetuspto-grants-2000_08
ORD IDord-5c78478023674d2397a473ce0806585d
Source noteuspto-grants-2000_08