Acetone → 6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)-4-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)quinazoline
Reaction equation
[C:33](=[O:34])([O-:35])[O-:36].[CH3:46][C:47](=[O:48])[CH3:49].[CH3:50][OH:51].[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][CH2:21][CH2:22]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12.[Cl:52][CH2:53][Cl:54].[K+:37].[K+:38].[Na+:40].[O:41]=[CH:42][N:43]([CH3:44])[CH3:45].[OH-:39].[OH:23][c:24]1[cH:25][c:26]2[c:27]([n:28][cH:29]1)[nH:30][cH:31][cH:32]2>>[c:2]1([O:23][c:24]2[cH:25][c:26]3[c:27]([n:28][cH:29]2)[nH:30][cH:31][cH:32]3)[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][CH2:21][CH2:22]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12Participants
11
Reactant 10
Product 1
Sources & evidence
- ORD record
- ord-8c6f143e133e4d52b171432bf1afee83
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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