Zaltoprofen → HCID 9883399, compound

Participants

Reaction Steps

Preparation-I of the invention for preparing Zaltoprofen is characterized in that 2-(4-amino-3-carboxymethylphenyl)propionic acid or its salt is diazotized and then reacted with thiophenol to give 2-(3-carboxymethyl-4-phenylthiophenyl)propionic acid or its salt, and the resulting product is then subjected to cyclization reaction. Preparation-I is illustrated in the following reaction scheme I: ##STR7## 1) Preparation of 2-(3-carboxymethyl-4-phenylthiophenyl)propionic acid or its salt

Provenance & Evidence