反应详情

1.0 g (2.69 mmol) of 2-(propenyl)-5-[4-(4-propylcyclohexyl)phenyl]selenophene is hydrogenated in 10 ml of ethyl acetate, in the presence of Pd/C (5% of Pd) at atmospheric pressure and RT. The reaction soln. is filtered and concentrated to dryness, and the crude product is purified by column chromatography (SiO2, n-heptane→n-heptane:EtOAc=20:1). The further purification is carried out by recrystallisation from n-heptane. 2-Propyl-5-[4-(4-propylcyclohexyl)phenyl]selenophene is obtained as a colourless solid.

1. filtrationis filtered
2. concentrationconcentrated to dryness
3. customthe crude product is purified by column chromatography (SiO2, n-heptane→n-heptane:EtOAc=20:1)
4. customThe further purification
5. customis carried out by recrystallisation from n-heptane