Triethylamine → HCID 68484012, compound

HRID 1873458Notes

Reaction equation

HRID 1873458 reaction equation
[CH3:1][CH:2]1[CH:7]=[C:6]([CH3:8])[CH2:5][CH2:4][C:3]1([C:12](=[O:16])[CH2:13][CH:14]=[CH2:15])[C:9]([CH3:11])=[CH2:10].C(N(CC)CC)C>C(Cl)Cl>[CH3:1][CH:2]1[CH:7]=[C:6]([CH3:8])[CH2:5][CH2:4][C:3]1([C:12](=[O:16])[CH:13]=[CH:14][CH3:15])[C:9]([CH3:11])=[CH2:10]

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 68478251HCID 68478251, compound

Product 1

HCID 68484012HCID 68484012, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 1-(2,4-dimethyl-1-(prop-1-en-2-yl)cyclohex-3-enyl)but-3-en-1-one (2.5 g, 11.5 mmol) and triethylamine (2 g) in CH2Cl2 was stirred at room temperature over night. The solvent and excess of triethylamine were evaporated and the residue distilled bulb-to-bulb to yield the title compound (80%) as a slightly yellow oil.

Workup

  1. customThe solvent and excess of triethylamine were evaporated
  2. distillationthe residue distilled bulb-to-bulb

Sources & evidence

ORD record
ord-265f1ff8fa504180a67b90b8574dd457
Source dataset
uspto-grants-2012_11
Patent number
US08304380B2

Reaction notes

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