Hydrochloric Acid → HCID 24958338, compound

Participants

Reaction Steps

40 mg (0.07 mmol) of the compound from Example 18A are dissolved in 0.9 ml of dioxane, and 0.9 ml of a 4 M solution of hydrogen chloride in dioxane are added. The reaction mixture is stirred at RT for 2 h and then directly purified by preparative HPLC (column: YMC GEL ODS-AQ S-5, 15 μm; mobile phase gradient: acetonitrile/water 10:90→95:5).

Provenance & Evidence