HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-1-butanol, (+)- → HCID 66916241, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-1-butanol, (+)- | HCID 120084 | — |
| Reactant | (S)-4-(4-Amino-2-fluorophenoxy)-N-(1-hydroxybutan-2-yl)-7-methoxyquinoline-6-carboxamide | HCID 66916390 | — |
| Reactant | HCID 86650701 | HCID 86650701 | — |
| Product | HCID 66916241 | HCID 66916241 | 81% |
Reaction Steps
Similar to the synthesis of compound 1, from compound 39c (300 mg), DMTMM•n-hydrate (329 mg), and (S)-2-aminobutan-1-ol (113 μL), compound 41a was yielded (297 mg, yield: 81%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304427B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-562fc70197df478495640a762edca334 |
| Source note | uspto-grants-2012_11 |