反应详情

6-Methoxyindazole-3-carboxylic acid (1.015 g; manufactured by Chem Pacific) was dissolved in hydrobromic acid (52 mL; manufactured by Kanto Chemical Co., Inc.), and stirred overnight at reflux. After cooling to room temperature, disappearance of the reacting material and generation of the target compound was confirmed based on LCMS. The solvent was evaporated under reduced pressure to obtain the target compound as a crude product (1.504 g).

1. temperatureat reflux
2. customThe solvent was evaporated under reduced pressure