HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 67005461, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Trimethyl orthobeznoate | HCID 69720 | — |
| Reactant | 2-Oxindole-6-carboxylic acid methyl ester | HCID 3734372 | — |
| Product | HCID 67005461 | HCID 67005461 | — |
Reaction Steps
Alternatively, the 6-methoxycarbonyl-2-oxindole may be reacted directly with trimethylorthobenzoate in the presence of acetanhydride to obtain the “enolether” (methyl 3-[methoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate). This alternative embodiment is described in the General Synthesis Scheme as step II′ and may be carried out as described above for step IIb.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08304541B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-67b4fde467b84c23acc09f2c555c6fb2 |
| Source note | uspto-grants-2012_11 |